29th January – 1st February 2018 | Paris, France

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Pre-Conference Workshop Day – Monday 29th January

WORKSHOP A: GENE THERAPY FOR THE MICROBIOME: A NOVEL THERAPEUTIC INTERVENTION

9.00am-12.00pm

Workshop A Speakers

While our knowledge of how bacteria of the human body communicate and interact within the whole organism is still evolving, the ability to modify the human microbiome represents a novel way to improve human health and ameliorate diseases. Currently, fecal microbiota transplantation, the use of pre- and pro-biotics, small molecules and biologics are being develop for this intent.

By using new research in genetic engineering, it’s now possible to look at the microbiome in a different way. This workshop will introduce the concepts for utilization of the commensal microbiome as a powerful mechanism for therapeutic intervention. Discussion will focus on the advantages and challenges of targeted delivery of therapeutic nucleic acids to bacteria inhabiting specific anatomical sites. A description of the microbial gene therapy platform technology being developed at SynPhaGen and potential therapeutic applications of the platform will be presented.

Join two leading researchers in industry to truly understand how gene therapy can be leveraged to help unlock the therapeutic potential of commensal microorganisms that reside in the human body.

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WORKSHOP B: HARNESSING THE SKIN MICROBIOME TO TREAT DISEASE

1.00pm-4.00pm

 Workshop B speakers

The skin microbiome plays a fundamental role in human health, protecting against pathogens and antigens while bolstering cutaneous immunity. Imbalances in the skin microbiome (i.e. “dysbiosis”) are highly associated with severity of skin disease, and research shows that improving the skin microbiome may be a promising approach to treating disease

Novel strategies have emerged to harness the skin microbiome to treat a plethora of diseases. These approaches vary and employ a plethora of techniques to beneficially modulate the skin microbiome or deliver therapeutic molecules to the skin. However, no topical microbiome-based therapy has been approved by major regulatory agencies worldwide.

Join this workshop to understand the latest in microbiome-based strategies for treating disease, key translational challenges to commercializes these approaches, and success stories in moving the needle forward in bringing new skin microbiome approaches to the market.

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