HyGIeaCare® offers a unique path for innovation in the microbiome field. It leverages its patent-protected  HygiSample^SM, and its access to inner-colonic microbiome of populations that reflect a wide range of prevalent diseases. The HygiSample microbiome signature is profoundly different than that of stool samples. Adding HygiSample effluent analytics to the current stool-based research can enhance the probability of success of drugs and biomarkers development, and personalized patient stratification for clinical purposes.